Antibiotic allergies are commonly reported among patients, but most do not experience reactions on rechallenge with the same agents. These reported allergies complicate management of infections in patients labelled as having penicillin allergy, including serious infections where penicillin-based antibiotics are the first-line (most effective and least toxic) treatment option. Allergy labels are rarely questioned in clinical practice, with many clinicians opting for inferior second-line antibiotics to avoid a perceived risk of allergy. Reported allergies thereby can have significant impacts on patients (...) and public health, and present major ethical challenges. Antibiotic allergy testing has been described as a strategy to circumvent this dilemma, but it carries limitations that often make it less feasible in patients with acute infections or in community settings that lack access to allergy testing. This article provides an empirically informed ethical analysis of key considerations in this clinical dilemma, usingStaphylococcus aureusbacteraemia in patients with penicillin allergies as a case study. We argue that prescribing first-line penicillin-based antibiotics to patients with reported allergies may often present a more favourable ratio of benefits to risks, and may therefore be more ethically appropriate than using second-line drugs. We recommend changes to policy-making, clinical research and medical education, in order to promote more ethically acceptable responses to antibiotic allergies than the status quo. (shrink)

ObjectiveCancer and its treatments affect patients’ fertility potential. This study examined the prevalence of reproductive concerns and their relationship with metacognitions among Chinese young adult female cancer survivors.MethodsA total of 318 YAFCS completed an online survey from March to December 2021. Participants reported sociodemographic characteristics, reproductive concerns and metacognitions. Reproductive concerns were measured using the Reproductive Concerns after Cancer scale, and metacognitions were measured by the Short Form of Metacognitions Questionnaire. We used Pearson correlation analysis to examine associations between metacognitions (...) and reproductive concerns across multiple domains and multivariable linear regression to determine the influencing factors of reproductive concerns.ResultsThe mean score of reproductive concern among YAFCS was 49.97 ± 12.52. A total of 57.9% of participants reported a high level of concern regarding at least one dimension of reproductive concerns, and they were most concerned about their child’s health and least concerned about partner disclosure of fertility status. We also found a moderate association between RCAC and MCQ-30 scores. In multivariate analyses, metacognitions, especially negative metacognitive beliefs had an impact on reproductive concerns among YAFCS.ConclusionHigher reproductive concerns were associated with higher metacognitions among YAFCS, especially with negative metacognitive beliefs. Oncology professionals should pay attention to assessing reproductive concerns in patients who want to have children or who have no children. Moreover, metacognitive beliefs may be an intervention target for alleviating reproductive concerns among YAFCS. (shrink)

Ben shu tong guo dui yu Li Zhuowu he Yangming xue de chan shi, dui yu Zhongguo qian jin dai bu tong yu xi fang de lu xiang jin xing le bian xi, ren wei"zai Zhongguo si xiang zhong cun zai zhe bu tong yu Ouzhou si xiang shi de zhan kai de Zhongguo du zi de si xiang shi de zhan kai", fan dui yi ban chang jian de, yi Ouzhou de li shi zhan kai (...) he jia zhi guan wei ji zhun de xi fang zhong xin lun li shi guan, cong er zai Zhongguo nei zai de si xiang li lu zhong xun zhao Zhongguo de"jin dai"ji qi"qu she yu fa zhan"; ta hai da po le zai Riben tong xing de dui yu Li Zhuowu tong xin shuo shi ge ren zhu yi biao xian de fu qian shuo fa, ba Li Zhuowu wan qi de fu za si xiang, te bie shi fo jiao si xiang zai ta shen shang de du te ti xian tui xiang dui yu ming dai si xiang ben shen de jie shi. (shrink)

本书从现代人的见地,以严格学术方法,论述了中世纪的思想文化,尤重其与现代思潮的关联。.

长期以来，清代有学术无思想，有思想无哲学，有哲学但很粗浅等看法似乎已成学界定论。本书是重新审视这些似是而非之定见的一部力作。作者通过在哲学史、思想史、学术史和新文化史多元写作方法之间自如切换，多维立体 地勾勒了乾嘉儒学声音低沉的义理建构与思想论争，以此呈现出乾嘉儒学生动丰赡的另一面。.

“国家教育部人文社会科学重点研究基地山西大学科学技术哲学研究中心”基金资助出版.

Ben shu gong fen wei liu zhang, qi zhu yao bao kuo: xu lun ; Shao Yong sheng ping ji qi zhu zuo wen ben kao bian ; Shao Yong xue shu si xiang de li shi bei jing ji yuan yuan ; Shao Yong xue shu si xiang yuan yuan; shao yong yi shu yu yi tu si xiang tan jiu deng nei rong.

本书内容包括:现代人本主义哲学教育思想、人本主义心理学教育思想、夸美纽斯教育思想、雅斯贝尔教育思想、马斯洛人本主义教育思想等。.

本书选辑了作者关于政治法律哲学的论文和政论,围绕民主、法治、公民权利和人文知识分子的良知等当代热点问题,联系中国的现实展开论述。.

Ben shu cong xi le mei xue wen ben jie du jiao du tan tao le xi le shen mei jiao yu si xiang. ben shu ren wei, xi le mei xue tong guo dui ren xing he mei de te xing ben zhi lian xi de chan shu, tong shi hui da le " ren shi shen me? " he " mei shi shen me? " zhe ge zi gu xi la yi lai yi zhi kun rao ren (...) de wen ti. (shrink)

本书在充分把握有关梁漱溟及其相关资料, 以及相关研究成果的基础上, 针对中国现代政治发展过程中所具有的十分复杂的政治、文化与教育的关系, 真切地还原了梁漱溟探索中国政治现代化之路的心路历程, 客观地评价了他的实践努力. 本书稿将时代与个人, 历史与逻辑较好地结合在一起, 既真实地反映了梁漱溟个人的政治变革追求随着时代发展变化的纵向历程, 也深入而较系统地对他每一阶段的思想和活动进行了专业性 (政治、文化和教育) 的评析, 展现了一定的历史发展的动态.

本书从生态文艺的基本观念到历史扫描,进而比较宏观地把握中国美学中的生态思想及中国古代艺术中生态性体验的特点,并由此通过对中国古代美学与艺术的生态特点的认识,通过对其理论及审美转换性的把握而引申至现代, 着力挖掘其现代意义及价值。.